同類書籍: Oncology, Dermatology

Advances in Melanoma, an Issue of Hematology/Oncology Clinic (Hardcover)
 

作者: David Fisher 
出版社: Elsevier Saunders
出版日期: 2009/06/18
尺寸: 229x155x15mm
重量: 499 grams
ISBN-10: 1437704883
ISBN-13: 9781437704884
書城編號: 1279215
 

原價: HK$780.00
現售: HK$741 節省: HK$39

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商品簡介
 
The field of melanoma biology has experienced a remarkable surge in recent years, owing to progress which has ranged from the most basic laboratory/preclinical discoveries to clinical developments that have begun to transform the management and prognosis for at least certain melanoma patients. Among the key areas that have contributed to this progress are studies relating to signaling and transcriptional pathways that regulate control over differentiation and survival of the melanocyte lineage. The identification of recurring activating mutations in specific signaling factors (B-RAF, N-Ras, c-KIT), amplification of other melanoma oncogenes (MITF, NEDD9), and the crucial recognition that certain of these genomic events occur within melanomas arising with specific clinical features (eg mucosal or acral origin) have led to clear recognition that melanoma is indeed many different diseases." While the various subclasses of melanoma may share common features, such as profound invasive and metastatic propensity, it is also likely that sharply focused therapeutic strategies may exploit the functionally critical molecular engines, which distinguish these subclasses. Certain strategies focus upon the immunogenicity and striking clinical opportunities afforded by immune modulation, while others focus more directly on tumor-specific targeting. This issue brings together some of the leaders who have contributed significant insights from basic melanoma biology to progress in the clinic.

David Fisher 作者作品表

eBook: Morality and the Bomb: An Ethical Assessment of Nuclear Deterrence (DRM PDF)
eBook: Morality and the Bomb: An Ethical Assessment of Nuclear Deterrence (DRM EPUB)
eBook: Cultural Theory and Psychoanalytic Tradition (DRM PDF)
eBook: Cultural Theory and Psychoanalytic Tradition (DRM EPUB)
Complete Photo Guide to Soap Making (Paperback)
eBook: Romain Rolland and the Politics of the Intellectual Engagement (DRM PDF)
eBook: Romain Rolland and the Politics of the Intellectual Engagement (DRM EPUB)
eBook: Complete Photo Guide to Soap Making (DRM EPUB)
Bill O'Reilly's Legends and Lies: The Civil War (Hardcover)
Bill O'Reilly's Legends and Lies: The Patriots (hardcover)
Bill O'Reilly's Legends and Lies: The Real West
eBook: Secret Life of Kim Dotcom: Spies, Lies and the War for the Internet (DRM EPUB)
Doctor Who and the Leisure Hive (Hardcover)
Morality and War (Paperback)
Doctor Who Androids of Tara (Hardcover)
eBook: Morality and War: Can War be Just in the Twenty-first Century? (DRM PDF)
eBook: Morality and War: Can War be Just in the Twenty-first Century? (DRM EPUB)
Morality and War (Hardcover)
eBook: Much Ado about (Practically) Nothing: A History of the Noble Gases (DRM PDF)
eBook: Much Ado about (Practically) Nothing: A History of the Noble Gases (DRM EPUB)

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