Medical and Surgical Therapy for Advanced Heart Failure in the Modern Era provides a comprehensive and in-depth review of important topics in both medical and surgical therapy of heart failure, with a special focus on recent and significant advancements in the field. Sections review updated epidemiology, pathophysiology and clinical approaches to advanced heart failure, medical and surgical therapies, and controversies and modern advancements in the field. Topics include advancements in our understanding and treatment of patients supported with ventricular assist devices, including protocols for gastrointestinal bleeding, blood pressure management, anticoagulation practices, and management of valvular disease during LVAD support. The book includes the use of Entresto, a novel agent used in heart failure and the use of remote monitoring such as the Cardiomems system. From a surgical standpoint, there are new technologies in this space, including fully implantable LVADs on the horizon, and the Sherpapak system for maintaining cold temperature during donor organ transport.