Sarcoidosis represents a major challenge for physicians - not just in respiratory medicine, but across a range of specialties. This book, with a multi-disciplinary authorship of the highest standard, presents the most up to date thinking on all aspects of the condition, from epidemiology to clinical manifestations and treatment options. Full coverage is given to both respiratory and non-respiratory aspects; the basic science that underlies the disease and its progression is evaluated in detail, and placed into its correct clinical context. Possible future advances are covered in a concluding section.

The editors - all leading figures in the field with international reputations - have compiled the definitive work on the subject in a single volume. The book is fully comprehensive and evidence-based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.

Contents

Historical survey

Definition

Epidemiology Aetiology

Pathology

Immunology

Genetics

The radiology of the lungs and the pleura

Intervention and radiological procedures

Lung function

Endoscopy

DEXA scanning

Nuclear medicine imaging

ECG; Holter monitoring; exercise tests

The heart, pericardium, large and small vessels

The upper respiratory tract

Asthma/irritable airways

Pulmonary fibrosis

The liver and gastrointestinal tract

The spleen, blood and bone marrow

The nervous system

The kidneys and calcium metabolism

Psychiatric aspects

Sarcoidosis of the skin

Ocular changes

Bones, joints and skeletal muscles

Superficial lymphadenopathy

The endocrine glands

Sarcoid/HIV and AIDS

Sarcoid/relationship to neoplasm/chemotherapy [including isolated breast lesions]

Sarcoid/antibody deficiency syndromes

Concomitant or associated disorders

Pulmonary and extrapulmonary involvement bdosis in childhood

Diagnosis of sarcoidosis: history, physical examination, presumptive diagnosis without biopsy, sources of biopsy material, utilisation of investigations and imaging

Treatment of sarcoidosis:

Surgical investigation and management

Pulmonary/cardiac transplantation

Physiotherapy in sarcoidosis

Rehabilitation

Immunisation/vaccination

Future progress in investigations and management

Author Bio

Donald N Mitchell MD FRCP

Hon Consultant Physician

Royal Brompton and University College Hospitals

London, UK

David R Moller MD

Professor of Medicine and Director

Sarcoidosis Clinic and Research Program

Department of Medicine

The Johns Hopkins University School of Medicine

Baltimor...