The nanosciences encompass a variety of technologies ranging from particles to networks and nanostructures. For example, nanoparticles have been proposed to be suitable carriers of therapeutic agents whilst nanostructures provide suitable platforms and scaffolds for sub-micro bioengineering. This book focuses on nanomedicine and nanotechnology as applied to the nervous system which includes the brain and peripheral nervous system. It covers safety, nanostructures, nanoparticle-based immunoassays, nanofiber microbrush arrays, nanoelectrodes, protein nanoassemblies, nanoparticles-assisted imaging, nanomaterials and ion channels, stem cell imaging, neuronal performance, treatment of stroke and spinal cord injury, lipid nanostructures, and many other areas.

Contents

General Aspects

Safety of Carbon Nanotubes for Neuronal Tissue, Giuseppe Bardi

Nanoparticle-based Immunoassays and their Applications in Nervous System Biomarker Detection, Chunping Jia, Qinghui Jin, and Jianlong Zhao

Electrical Stimulation of Brain Tissue with Carbon Nanofiber Microbrush Arrays, Edward de Asis, Russell J. Andrews, and Jun Li

Nanoelectrode Arrays for Monitoring and Modulating Nervous System Electrical and Chemical Activity, R.J. Andrews

Probing Protein Nanoassemblies in Neurodegenerative Disease, Min S. Wang and Michael R. Sierks

Nanoparticle-assisted Laser Desorption/ionization (nano-PALDI)-based Imaging Mass Spectrometry (IMS) and its Application to Brain Sciences, S. Hameed, Yuki Sugiura, Yoshishige Kimura, K.K. Shrivas, and Mitsutoshi Setou

Nanomaterials and Ion Channels: Observed Effects and Possible Mechanisms, Lorin M. Jakubek and Robert H. Hurt

Biomolecular Engineering for the Regulation of Alpha-synuclein Nanostructure toward the Development of Alpha-synuclein Targeting Nanomedicine, Natsuki Kobayashi, Jihoon Kim, and Koji Sode

Nanomaterials for Stem Cell Imaging in the Central Nervous System, A. Solanki, S. Shah, Michael H. Koucky, and Ki-Bum Lee